Vitrification uses a new cell culture system and very rapid ‘flash’ freezing that is designed to protect eggs from injury during the egg freezing/thawing process. This technology may enable us to freeze mature eggs with the possibility of good survival after thawing and get good fertilization and pregnancy rates once they are thawed.
Egg freezing is still considered experimental by the American Society for Reproductive Medicine but by applying the new advances in cryopreservation, many groups, including our own early data with egg vitrifcation and thawing, have realized a sharp increase in survival rates of the eggs once thawed (approximately 90%) and subsequent fertilization rates (as high as 80%). These egg freezing improvements have led to pregnancy rates from frozen eggs from women younger than 35 years of age similar to pregnancy rates in cycles in which the eggs were not frozen. Women interested in freezing their eggs can now consider the option of waiting until they wish to conceive at a later date of their own choosing.